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Extracts were obtained from the synovium of affected knees of 8 rheumatoid arthritis (RA) patients and 11 osteoarthritis (OA) patients using the buffer for the dissociation of antigen/antibody immunocomplex, and the assay for anti-citrullinated type II collagen antibodies was performed. The transverse line shows the cutoff value. For all samples from RA patients, an inhibition assay was performed using citrullinated type II collagen as antigen
