Table 3. Association between clinical parameters and placental cytokines in HIV-1 positive women.
Ruptured membranes (≥4h) | CD4 | Viral load | NVP administration before delivery | Infection other than HIV | Parity | Number of previous Pregnancies | Pregnancy duration | Birth weight | |
Correlation (p-value) | Correlation (p-value) | Correlation (p-value) | Correlation (p-value) | Correlation (p-value) | Correlation (p-value) | Correlation (p-value) | Correlation (p-value) | Correlation (p-value) | |
TNF-α transcript | positive (0.02) | positive (0.02) | (NS) | (NS) | (NS) | (NS) | (NS) | (NS) | (NS) |
TNF-α protein | negative (0.05) | negative (0.004) | negative (0.01) | (NS) | (NS) | positive (0.04) | positive (0.03) | (NS) | (NS) |
TNF-α undetectable | (NS) | positive (0.04) | positive (0.008) | positive (0.007) | (NS) | negative (0.005) | negative (0.004) | (NS) | (NS) |
IL-8 protein | (NS) | (NS) | (NS) | (NS) | (NS) | (NS) | (NS) | negative (0.002) | (NS) |
IL-16 protein | (NS) | (NS) | (NS) | (NS) | positive (0.03) | (NS) | (NS) | (NS) | (NS) |
LIF protein | (NS) | (NS) | negative (0.004) | (NS) | (NS) | (NS) | (NS) | (NS) | (NS) |
LIF undetectable | (NS) | (NS) | (0.003) | (NS) | (NS) | (NS) | (NS) | (NS) | (NS) |
IL-15 protein | (NS) | (NS) | (NS) | negative (0.05) | (NS) | (NS) | (NS) | (NS) | (NS) |
IL-7 protein | (NS) | (NS) | (NS) | (NS) | (NS) | (NS) | (NS) | (NS) | negative (0.03) |
RANTES protein | (NS) | (NS) | positive (0.05) | (NS) | (NS) | (NS) | (NS) | (NS) | (NS) |
NS: not significant. See Methods section for P-value calculation.