Fig. 3.

Cochlear cells lacking Bak are resistant to PQ-induced apoptotic cell death. (A) Cochlear cell viability (%) and neuron viability (%) were measured after PQ treatment of cells derived from 4-d-old WT and Bak^−/− mice (n = 3). (B) TUNEL-positive cells were counted after PQ treatment (400 μM) of cells derived from 4-d-old WT and Bak^−/− mice (n = 3). (C) Relative cochlear mRNA expression of Bak was measured after PQ treatment (400 μM) of cells derived from 4-d-old WT and Bak^−/− mice (n = 3). *Significantly different from WT (P < 0.05). **Significantly different from control (P < 0.05). Error bars represent SEM.