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. 2009 Nov 9;106(46):19432–19437. doi: 10.1073/pnas.0908786106

Fig. 5.

Fig. 5.

Enhancing antioxidant defenses reduce oxidative DNA damage and reduce Bak expression in the cochlea. (A) Oxidative damage to DNA (8-oxodGuo) was measured in the cochleae from WT and MCAT mice at 13 months of age and from WT mice at 5 and 15 months of age (n = 5–10). (B) Relative cochlear mRNA expression of Bak and Bax was measured in the cochleae from WT mice at 5 and 15 months of age (n = 5). (C) Relative cochlear mRNA expression of Bak and Bax was measured in the cochleae from WT and MCAT mice at 13 months of age (n = 5). *Significantly different from control diet or WT mice (P < 0.05). Error bars represent SEM.