FIG. 3.

Change from basal hepatic gluconeogenic flux to G6P and net hepatic glycogenolytic flux in 60-h fasted conscious canines during the basal (−40 to 0 min) and experimental (0–300 min) periods (means ± SEM; n = 5, 5, and 6 in control, 4×, and 16× groups, respectively; *P < 0.05 vs. control group; †P < 0.05 vs. basal period). Basal rates of GNG flux were 1.40 ± 0.26, 1.14 ± 0.16, and 1.56 ± 0.26 mg · kg⁻¹ · min⁻¹, respectively.