TABLE 3.

Results from homeostasis model assessment of insulin resistance, peripheral and hepatic insulin secretion disposition index (D_i-peripheral and D_i-hepatic)

	Before bed rest		After bed rest
	FDR group	CON group	FDR group	CON group
n	13	20	13	20
Basal HOMA-IR*	1.0 ± 0.3	0.8 ± 0.3	1.6 ± 0.7†	1.1 ± 0.5†‡
Di-peripheral (10−3 × pmol · l−1 · min−1 · mg−1 · min−1 · kg FFM−1)*	28.9 ± 20.9	27.4 ± 15.9	34.8 ± 33.5	32.7 ± 17.6
Di-hepatic (pmol · l−1 · min−1 · μmol−1 · min−1 · kg FFM−1 · pmol−1 · l−1)*	4.1 ± 1.8	11.5 ± 16.9§	4.5 ± 2.9	9.6 ± 6.3‡

Data are means ± SD.

*Log-transformed data.

†Significant difference before vs. after bed rest; P < 0.05.

‡Significant difference between FDR and CON groups after bed rest, P < 0.05.

§Significant difference between FDR and CON groups before bed rest, P < 0.05. D_i-hepatic, measure for hepatic insulin action; D_i-peripheral, peripheral disposition index, measure for peripheral insulin action; HOMA-IR, homeostasis model assessment of insulin resistance.