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. 2009 Aug 20;58(12):2910–2919. doi: 10.2337/db08-0506

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© 2009 American Diabetes Association

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 5. — Effect of PD153035 on tissue protein levels of TNF-α, IL-6, and iNOS and arginase activity in adipocytes and SVF from retroperitoneal adipose tissue. Representative blots show the tissue levels of TNF-α, IL-6, iNOS, EGRF tyrosine phosphorylation, EGRF, Caveolin, and Cd68 protein expression in adipocytes (A–D) and TNF-α, IL-6, iNOS, EGRF tyrosine phosphorylation, EGRF, Cd68, and actin protein expression in the SVF (F–J). K: Arginase activity of adipocytes and SVF from control mice, HFD mice, and HFDPD 1 and 14 days. Serum levels of adiponectin (L), TNF-α (M), leptin (N), and IL-6 (O) and MCP-1 (P), MCP-2 (Q), and MCP-3 (R) protein expression were obtained using ELISA assay. Data are presented as means ± SE of six to eight mice per group. *P < 0.05 vs. control group; #P < 0.05 vs. HFD group.