TABLE 5.
Reference | Patients, n | Mean age, years | Men, % | Assessability, % | Sensitivity, % | Specificity, % | NPV, % | PPV, % | Diagnostic accuracy, % | Positive likelihood ratio | Negative likelihood ratio |
---|---|---|---|---|---|---|---|---|---|---|---|
16-slice MDCT | |||||||||||
Martuscelli et al (64) | 96 | 62 | 83 | 88 | 97 | 100 | 99 | 100 | 99 | Undefined | 0.0 |
Chiurlia et al (65) | 52 | 63 | 87 | 99 | 99 | 100 | 95 | 100 | 99 | Undefined | 0.0 |
Moore et al (70)*† | 50 | 63 | 78 | 97 | 100 | 99 | 100 | 98 | 99 | 100 | 0.0 |
Anders et al (68) | 32 | 67 | 91 | 100 | 95 | 89 | 96 | 86 | 91 | 8.6 | 0.1 |
Total | 230 | 94 | 98 | 98 | 99 | 98 | 98 | 25.0 | 0.0 | ||
64-slice MDCT | |||||||||||
Meyer et al (71) | 138 | 68 | 88 | 98 | 97 | 97 | 99 | 93 | 97 | 32.3 | 0.0 |
Onuma et al (60) | 54 | 65 | 81 | 95 | 100 | 98 | 100 | 94 | 99 | 50 | 0.0 |
Malagutti et al (73) | 52 | 65 | 87 | 100 | 100 | 98 | 100 | 98 | 99 | 50 | 0.0 |
Jabara et al (61) | 50 | 64 | 90 | 99 | 100 | 100 | 100 | 100 | 100 | Undefined | 0.0 |
Ropers et al (62) | 50 | 67 | 76 | 100 | 100 | 94 | 100 | 76 | 95 | 16.7 | 0.0 |
Feuchtner et al (63) | 40 | 62 | 80 | 100 | 85 | 95 | 97 | 80 | 93 | 17.0 | 0.2 |
Pache et al (72) | 31 | 68 | 84 | 97 | 98 | 89 | 98 | 90 | 94 | 8.9 | 0.0 |
Total | 415 | 98 | 98 | 97 | 99 | 92 | 97 | 32.3 | 0.0 |
Bypass graft stenosis was defined as >50% luminal narrowing of vessel. All studies assessed bypass graft stenosis with quantitative CCA.
Blinding was not specified;
Beta-blockers were not administered for heart rate reduction. NPV Negative predictive value; PPV Positive predictive value