TABLE 6.

Summary of weighted analysis for 16-slice, 40-slice and 64-slice multidetector computed tomography (MDCT)

Assessment	Patients, n	Assessability, %	Sensitivity, %	Specificity, %	NPV, %	PPV, %	Diagnostic accuracy, %	Positive likelihood ratio	Negative likelihood ratio
16-slice MDCT
Stenosis in suspected CAD	1193	92	88	96	98	73	95	22.0	0.1
In-stent restenosis	284	72	73	95	94	94	94	14.6	0.3
Post-CABG occlusion	297	94	100	98	99	92	98	49	0.0
Post-CABG stenosis	230	94	100	96	100	94	98	25.0	0.0
40-slice MDCT
In-stent restenosis	65	64	74	96	78	83	92	58	81
64-slice MDCT
Stenosis in suspected CAD	957	97	89	96	98	79	95	22.3	0.1
In-stent restenosis	615	88	92	92	97	75	92	11.5	0.1
Post-CABG occlusion	194	98	100	100	100	98	99	Undefined	0.0
Post-CABG stenosis	415	98	98	97	99	92	97	32.3	0.0

Coronary artery or bypass graft stenosis was defined as >50% luminal narrowing of vessel. All studies assessed vessel stenosis or occlusion with quantitative or visually based catheter-based coronary angiography. CABG Coronary artery bypass graft; CAD Coronary artery disease; NPV Negative predictive value; PPV Positive predictive value