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Reduced migration caused by signaling pathway inhibitors. A similar experiment to that described in Figure 4 was performed, except that spleen cells from IRBP1–20-immunized B6 mice were attracted to the lower chamber containing supernatants collected from RACs pretreated with medium or IL-17 (100 ng/ml) in the absence or presence of the indicated signaling pathway inhibitors for 24 h. The results are representative of those obtained in three experiments. **, P < 0.01.
