Table 1.
Ability of biological and previous caries variables to predict caries
| Caries Y matricesa | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | Increment | Incidence | Progression | ||||||
| X matricesa | [n variables]b | R2 | Q2 | R2 | Q2 | R2 | Q2 | R2 | Q2 |
| Primary models (all VIPs) | |||||||||
| Plaque, diet, saliva | [88] | 0.597 | 0.260M1 | 0.619 | 0.084 | 0.534 | 0.056 | 0.632 | 0.034 |
| Plaque, diet, saliva + previous caries | [88 + 18] | 0.567 | 0.211M2 | 0.406 | 0.164M3 | 0.365 | 0.162M4 | ||
| Secondary models (VIPs > 1.0) | |||||||||
| Plaque markers | [6,4,6,4] | 0.353 | 0.289 | 0.218 | 0.142 | 0.181 | 0.097 | 0.286 | 0.226 |
| Diet markers | [7,9,9,0] | 0.155 | 0.113 | 0.303 | 0.153 | 0.170 | 0.083 | ntc | ntc |
| Saliva markers | [5,5,7,2] | 0.129 | 0.034 | nsd | nsd | nsd | nsd | ntc | nt |
| Multimarkers (n = 6-39) | |||||||||
| Plaque, diet, saliva | [18,18,22,6] | 0.528 | 0.404 | 0.377 | 0.224 | 0.351 | 0.204 | 0.311 | 0.212e |
| Previous caries | [ ,17,17,16] | 0.382 | 0.323 | 0.287 | 0.247 | 0.494 | 0.421 | ||
| Plaque, diet, saliva + previous caries | [ ,35,39,22] | 0.662 | 0.354 | 0.418 | 0.318 | 0.511 | 0.386 | ||
| Five marker panelf | [5] | 0.430 | 0.275 | ||||||
| Single lactobacilli markerg | [1] | 0.340 | 0.270 | ||||||
a The primary models harbor all variables. The secondary models harbor influential (VIP > 1.0) markers from the corresponding primary models M1 to M4. All models had ≤ 3 significant components except for the model with a single saliva lactobacilli marker. The R2 (explanatory) and Q2 (predictive) values gives the performance of each PLS model (see Methods).
b Numbers of variables or markers in each separate PLS model.
c nt = not tested
d ns = no significant component.
e No available diet variable with VIP > 1.0.
f Saliva lactobacilli, plaque mutans streptococci, diet retinol and zinc, saliva calcium with high VIP-values.
g Saliva lactobacilli.