Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mean Percent Improvement From Baseline in Individual MADRS Items From Pooled Studies of Patients With Bipolar I and II Disorder Experiencing a Depressive Episode (MMRM)a
aP values based on change from baseline MMRM analyses.
*P < .05 versus placebo; †P < .01; ‡P < .001.
Abbreviations: MADRS = Montgomery-Asberg Depression Rating Scale, MMRM = mixed-model repeated measure.
