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Least Squares Mean Change From Baseline in MADRS Total Score Stratified According to Baseline Anxiety Level From Pooled Studies of Patients With Bipolar I and II Disorder Experiencing a Depressive Episode (ITT, LOCF ANCOVA)
*P < .05 versus placebo.
†P < .01.
‡P < .001.
Abbreviations: HARS = Hamilton Rating Scale for Anxiety, ITT = intent-to-treat, LOCF ANCOVA = last-observation-carried-forward analysis of covariance, MADRS = Montgomery-Asberg Depression Rating Scale.
