Table 1.

spdo regulates Notch pathway activity in a numb-dependent manner

Genotype	Number of Svp-lacZ+ heart cells	P-value Number of Svp-lacZ− cardioblasts	P-value	Number of Eve+ pericardial cells	P-value
Wild type	28.1±0.5 (n=15)		37.9±0.9 (n=15)	-	-
o/e spdo	31.2±2.2 (n=15)	<0.0001*	47.9±4.9 (n=15)	<0.0001*	-	-
o/e spdo; numb2/+	27.6±2.2 (n=15)	<0.001†	39.2±1.8 (n=15)	<0.0001†	-	-
numb2	22.9±3.5 (n=20)		33.9±1.7 (n=20)		44.2±2.4 (n=20)
o/e spdo; numb2	8.6±3.1 (n=20)	<1×10−10‡	27.4±3.8 (n=40)	<1×10−5‡	18.7±9.0 (n=20)	<1x10−10‡

Numbers are given per bilateral side of an embryo; n refers to the number of embryos scored. The P-value is derived by t-test. Values are given ± s.d. o/e spdo refers to twist-GAL4-mediated expression of UAS-Spdo^G14; UAS-Spdo^G1 transgenes.

^*Relative to wild-type embryos.

^†Relative to o/e Spdo embryos.

^‡Relative to numb mutant embryos.