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. 2009 Dec 4;4(12):e8149. doi: 10.1371/journal.pone.0008149

Figure 3. Effect of PDGF and VEGF receptor kinase inhibitors on desmin-positive pericyte coverage.

Figure 3

Sections of KAT-4 tumors from mice treated with vehicle, STI571 or PTK/ZK, alone or in combination were stained with antibodies against the pericyte marker desmin. The number of desmin-positive pericytes per vessel perimeter (panel A) or per number of vessels (panel B) were quantified. Data are presented as means +/− SEM. Statistically significant differences (p<0.05) compared to control (vehicle treatment;*), compared to PTK/ZK 2 days (#), and compared to STI571 4 days (§), are indicated.