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. 2009 Dec 4;4(12):e8149. doi: 10.1371/journal.pone.0008149

Figure 4. Effect of PDGF and VEGF receptor kinase inhibitors on KAT-4 tumor cell proliferation and apoptosis.

Figure 4

Sections of KAT-4 tumors from mice treated with vehicle, STI571 or PTK/ZK, alone or in combinations, were stained for Ki67 (panel A) and cleaved caspase-3 (panel B) to monitor proliferation and apoptosis, respectively. Data are presented as means +/− SEM. Statistically significant differences (p<0.05) compared to control (vehicle treatment;*), and compared to PTK/ZK 2 days (#), are indicated.