Table IV -.
Effect of controlling for IL-6, TNF-α, or oxLDL on the adjusted associations of vBMD measures with incident in white men, the Health, Aging, and Body Composition Study.
BMD | N at risk (events) | Adjusted for risk factors*Hazard Ratio (95% CI) | Adjusted for risk factors + IL-6, TNF-α, or oxLDL**Hazard Ratio (95% CI) |
---|---|---|---|
Integral vBMD | |||
IL-6 | 280 (62) | 1.37 (1.01-1.86)a | 1.38 (1.02-1.88)a |
TNF-α | 276 (63) | 1.40 (1.04-1.89)a | 1.40 (1.04-1.89)a |
oxLDL | 292 (66) | 1.39 (1.04-1.87)a | 1.41 (1.05-1.89)a |
Cortical vBMD | |||
IL-6 | 280 (62) | 1.37 (1.02-1.85)a | 1.38 (1.02-1.86)a |
TNF-α | 276 (63) | 1.39 (1.03-1.86)a | 1.38 (1.03-1.85)a |
oxLDL | 292 (66) | 1.39 (1.04-1.85)a | 1.41 (1.05-1.88)a |
Models in men were adjusted for: age, study site, education, physical activity, Health ABC physical performance score, BMI, HDL, LDL, systolic blood pressure, glucose level, history of hypertension, and use of diabetes drugs.
oxLDL models did not include LDL level due to the high correlation between the two measures.
p<0.05