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Schematic picture of the osteoblastogenesis process. Osteoblasts (OBL) arise from mesenchymal stem cells (MSC) which under proper stimuli are committed toward an osteo/chondro-progenitor (osteo/chondro-prog.), followed by an osteoprogenitor cell (Osteo-prog.), a pre-osteoblast (pre-OBL) expressing alkaline phosphatase (ALP) and an active, mature osteoblast which secretes bone matrix proteins.
