Table I - .

List of Abbreviations.

6MP = 6-mercaptopurine

CISH = Chromogenic In Situ Hybridization

CYP2C9 = Cytochrome P450 2C9 enzyme

CYP2D6 = Cytochrome P450 enzyme 2D6

EC = European Commission

EU = European Union

FISH = Fluorescent In Situ Hybridization

G6PD = Glucose 6-Phosphae Dehydrogenase

HLA = Human Leukocyte Antigen

ICH = International Conference on Harmonization

IHC = Immunohistochemistry

PGt = Pharmacogenetics

PGx = Pharmacogenomics

SNPs = Single Nucleotide Polymorphisms

TPMT = Thiopurine S-methyl-transferase enzyme

VKORC1 = Vitamin K epoxide Reductase Complex-subunit1