Table 4.
Survey of services available for LGMD gene mutations
| Laboratory | Gene Panel | Genes Tested | Pricing | TAT |
|---|---|---|---|---|
| Athena Dx Worcester, MA | Yes (9 genes) |
CAPN3, SG's, DYSF, CAV3, FKRP, LMNA | $10,790.00 (total) |
5-6 weeks |
| Nationwide Children's Ohio State | No | CAPN3, SG's, DYSF, CAV3, FKRP, LMNA | $874.50-$1790.75 (per gene) (varies by size) |
4 weeks |
| Prevention Genetics Marshfield, WI | No | CAPN3, DYSF, FKRP, LAMA2, SGCA, SGCB (6 genes singly sequenced) |
$390.00-$2990.00 (per gene) (varies by size) |
40 days/gene |
| U. of Utah | Yes (2 genes) | DYSF & CAPN3 | $1500.00 (total) |
8 weeks |
| U of Iowa | Yes (3 genes) (panel)* |
SGCA, SGCB, FKRP CAPN3, LMNA, FKRP, POMT1, POMT2, POMGnT, FCMD** |
$905panel* $462-1781 (per gene) (varies by size) |
2-4 wks |
Data gathered from GeneTests http://www.genetests.org and telephone survey of available services for LGMD gene testing. * The U of Iowa panel tests for three known mutations only, if none is positive then the entire FKRP gene is sequenced. **7 genes singly sequenced. (Note that the survey was done in April, 2009 and the services fortunately are constantly being expanded and improved.)