TABLE 4.
Percentage fatty acid composition of plasma membrane phospholipids of Treg cells purified from the mice spleen
Fatty Acids (% of Total) | Cells from Mice Fed Standard Diet | Cells from Mice Fed DHA Diet |
---|---|---|
C16:0 | 1.99 ± 0.31 | 2.16 ± 0.39 |
C16:1 | 27.01 ± 0.37 | 27.37 ± 0.20 |
C18:0 | 18.79 ± 0.25 | 18.31 ± 0.67 |
C18:1 | 13.15 ± 0.56 | 12.78 ± 0.75 |
C18:2n-6 | 11.12 ± 0.75 | 10.19 ± 0.11 |
C20:4n-6 (AA) | 25.67 ± 0.98 | 13.12 ± 0.28* |
C20:5n-3 (EPA) | 0.41 ± 0.05 | 6.09 ± 0.15* |
C22:6n-3 (DHA) | 1.77 ± 0.06 | 9.99 ± 0.41* |
The cells were purified from the spleen of mice fed a standard diet or DHA diet for 6 weeks. Values are mean ± SEM, n = 10 mice per group of diet. *P < 0.01, significant differences between DHA diet group and standard diet group. The distribution of the percentage of the fatty acid composition was statistically identical in Treg and Teff cells.