TABLE 3.
CKD (n = 10) | Controls (n = 20) | P | |
---|---|---|---|
Plasma concentrations (mg/l) | |||
VLDL apoB | 73.1 [17.2, 371.9] | 46.4 [23.7, 85.7] | 0.039 |
IDL apoB | 86.5 [39.6, 224.0] | 55.2 [11.7, 135.2] | 0.006 |
LDL apoB | 814.2 [581.6, 1070.7] | 839.9 [595.0, 1042.7] | 0.98 |
FCR (pools/day) | |||
VLDL apoB | 4.3 [0.63, 17.99] | 6.8 [4.3, 14.4] | 0.008 |
IDL apoB | 3.4 [1.0, 4.3] | 5.0 [2.2, 21.6] | <0.0001 |
LDL apoB | 0.39 [0.16, 0.49] | 0.45 [0.24, 0.76] | 0.31 |
Production rate (mg/kg/day) | |||
VLDL apoB | 14.4 [10.0, 31.0] | 17.0 [11.0, 25.5] | 0.18 |
IDL apoB | 13.6 [7.2, 18.2] | 13.6 [9.6, 25.3] | 0.53 |
LDL apoB | 12.7 [5.8, 22.0] | 14.9 [7.5, 24.4] | 0.13 |
Conversion rate (%) | |||
VLDL to IDL apoB | 71.7 [39.8, 96.5] | 70.4 [44.9, 99.9] | 0.71 |
IDL to LDL apoB | 92.2 [60.6, 100.0] | 99.1 [64.4, 100.0] | 0.14 |
Kinetic data presented as median [minimum, maximum].