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. 2009 Dec;50(12):2524–2531. doi: 10.1194/jlr.P900003-JLR200

TABLE 3.

Kinetic estimates of total VLDL, IDL, and LDL apoB-100 in the CKD and control subjects

CKD (n = 10) Controls (n = 20) P
Plasma concentrations (mg/l)
 VLDL apoB 73.1 [17.2, 371.9] 46.4 [23.7, 85.7] 0.039
 IDL apoB 86.5 [39.6, 224.0] 55.2 [11.7, 135.2] 0.006
 LDL apoB 814.2 [581.6, 1070.7] 839.9 [595.0, 1042.7] 0.98
FCR (pools/day)
 VLDL apoB 4.3 [0.63, 17.99] 6.8 [4.3, 14.4] 0.008
 IDL apoB 3.4 [1.0, 4.3] 5.0 [2.2, 21.6] <0.0001
 LDL apoB 0.39 [0.16, 0.49] 0.45 [0.24, 0.76] 0.31
Production rate (mg/kg/day)
 VLDL apoB 14.4 [10.0, 31.0] 17.0 [11.0, 25.5] 0.18
 IDL apoB 13.6 [7.2, 18.2] 13.6 [9.6, 25.3] 0.53
 LDL apoB 12.7 [5.8, 22.0] 14.9 [7.5, 24.4] 0.13
Conversion rate (%)
 VLDL to IDL apoB 71.7 [39.8, 96.5] 70.4 [44.9, 99.9] 0.71
 IDL to LDL apoB 92.2 [60.6, 100.0] 99.1 [64.4, 100.0] 0.14

Kinetic data presented as median [minimum, maximum].