Fig. 8.

A and B: effect of DPI and apocynin on oxalate-induced H₂O₂ generation (A) and LDH release (B). LLC-PK₁ cells were pretreated with 0.5 μM DPI or 0.5 mM apocynin for 30 min and then exposed to oxalate along with inhibitors for 3 h, after which H₂O₂ production and LDH release were determined. DMSO was used as a vehicle. Data are normalized to control, and values are expressed as means ± SE. Comparisons shown: a, significant compared with control; b, significant compared with oxalate; c, significant compared with DPI-treated control; d, significant compared with apocynin-treated control. *P < 0.05; n = 6.