Table 1.
Experimental Groups | n | Δ% Mean Arterial Pressure, mmHg | Δ% Heart Rate, beats/min | Δ% Iliac Blood Flow | Δ% Iliac Vascular Conductance |
---|---|---|---|---|---|
VX | 16 | −4.7±1.8* | 1.2±0.9 | 10.2±1.6* | 15.3±2.7* |
GX | 39 | −39.7±1.9* | 3.1±1.9 | 16.6±3.3* | 99.9±9.9* |
ATX | 15 | −49.2±2.8* | −13.9±3.5* | 8.6±6.1 | 125.1±18.2* |
Values are means ± SE. Abbreviations are as in Fig. 1. Numbers of responses to VX, GX, and ATX were combined from those protocols where these blockades were applied as a first pharmacological manipulation: nVX = nVX + nLX+VX; nGX = nADX+GX + nADX+GX+VX + nADX+GX+VX+ATX + n of respective controls; nATX = nATX + n of respective control (see Table 2). The small changes in mean arterial pressure and iliac vascular conductance caused by VX were allowed to return spontaneously toward resting levels, whereas the large, sustained changes in these variables caused by ATX and GX were compensated via intravenous infusion of phenylephrine.
P < 0.05 vs. zero.