Table 1.
Stage | Litters | Number of Embryos |
Phenotype Found in the Mutants |
|||
---|---|---|---|---|---|---|
Total | Mutant | Reverse Flow | Dead/Dying | Normal | ||
E11.5 | 10 | 82 | 23 (28%) | 12 (52%) | 3 (13%) | 8 (35%) |
E12.5 | 5 | 33 | 11 (33%) | 3 (27%) | 8 (73%) | 0 (0%) |
A total of 3 embryos out of 20 living mutants at embryonic day (E) 11.5 showed arrhythmia: 2 with arrhythmia and reverse blood flow (10%) and 1 with arrhythmia but with normal blood flow (5%). The 3 living mutant embryos at E12.5 showed normal rhythm.