TABLE 1.

Phospholipid composition of LUVs

	Lipid mole fraction						LUV radiusa	Estimated molecular weightb
	DOPC	DOPS	PtdIns(4,5)P2	PtdIns(3,4,5)P3
							nm
0.5% PtdIns(4,5)P2	0.995	0	0.0050	0			NDc	ND
2% PtdIns(4,5)P2	0.980	0	0.0200	0			42 ± 0.60	5.7 × 107
8% PtdIns(4,5)P2	0.920	0	0.0800	0			48 ± 4.0	8.0 × 107
2% PtdIns(4,5)P2 + 20% DOPS	0.780	0.200	0.0200	0			49 ± 4.7	8.8 × 107
2% PtdIns(3,4,5)P3	0.980	0	0	0.0200			35 ± 4.1	3.9 × 107

	POPE	POPC	POPS	PI	SM	PtdIns(4,5)P2	LUV radiusa	Estimated molecular weightb
0.5% PtdIns(4,5)P2 + lipid mixd	0.474	0.199	0.184	0.0920	0.0460	0.0050	ND	ND
2% PtdIns(4,5)P2 + lipid mixd	0.474	0.184	0.184	0.0920	0.0460	0.0200	52 ± 0.55	8.7 × 107

^a Values were determined from dynamic light scattering measurements. Errors are S.D. from three to four independent measurements.

^b Lipid compositions are as defined in Ref. (22).

^c ND indicates not determined.

^d Data are from Ref. (24).