Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Distinct binding at the three putative calcium-binding sites. A–C, the coordination of the calcium ions (Ca2+-M, Ca2+-D1, and Ca2+-D2) by ADAM22 residues and water molecules. D, thermodynamic profile of the binding between calcium and the EDTA-treated ADAM22 protein showing a 1:1 stoichiometry.
