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. 2009 Sep 7;284(45):30889–30896. doi: 10.1074/jbc.M109.049718

TABLE 1.

Mechanical measurements in isometrically contracted skinned TC fiber bundles from WT and NEB KO mice

Lines 1–5 were measured at pCa 4.3; lines 6 and 7 were measured at a pCa range of 8.5 to 4.3. NS means not significant.

WT NEB KO p value
1. Tension (mN/mm2) 84 ± 4 38 ± 2.2 <0.001
2. Stiffness (mN/mm3) 920 ± 23 388 ± 29 <0.001
3. Tension/stiffness (0.01 mm) 9.1 ± 0.4 9.7 ± 0.6 NS
4. ktr (s−1) 7.8 ± 0.3 4.7 ± 0.3 0.003
5. Tension cost (pmol mN−1 mm−1 s−1) 4.4 ± 0.3 5.9 ± 0.3 0.005
6. pCa50 5.90 ± 0.02 5.74 ± 0.01 <0.001
7. nH 4.38 ± 0.23 3.64 ± 0.14 0.02