TABLE 1.
Stokes radius r for 50 μm monomeric AS, 50 μm Hsp90, and soluble oligomers obtained by agitation of AS in the presence of Hsp90 (AS:Hsp90 = 1:2)
For preparations of mature fibrils, little residual monomeric AS and no higher sized species were detectable in solution after sample centrifugation (data not shown).
Stokes radius r | |
---|---|
nm | |
Monomeric AS | 3.0 ± 0.2a |
Hsp90 | 7.1 ± 0.6 |
AS agitated in the presence of Hsp90 | 14.8 ± 1.7 |
a Value reported in literature: 3.2 nm (41).