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. 2009 Aug 27;284(45):31303–31314. doi: 10.1074/jbc.M109.028910

FIGURE 4.

FIGURE 4.

12/15LO regulates macrophage cholesterol efflux. Control B6, LOKO, and LOTG bone marrow-derived macrophages were isolated and utilized in a cholesterol efflux assay as described under “Materials and Methods.” Cholesterol efflux to lipid-free apoA-I (apoA-I) and to HDL (HDL) for 4 or 8 h was assessed. Data represent the mean ± S.E. of 6 experiments (*, significantly lower than B6 HDL 4 h p < 0.0001; #, significantly higher than B6 HDL 4 h p < 0.05; $, significantly higher than B6 HDL 8 h p < 0.02; and &, significantly lower than B6 HDL 8 h p < 0.03 by ANOVA).