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. 2009 Sep 15;284(45):31463–31472. doi: 10.1074/jbc.M109.030213

FIGURE 4.

FIGURE 4.

Enhanced proliferation, degranulation, and cytokine production of WT, but not integrin αIIb-deficient, BMMCs through interaction with FB. A, cell numbers of WT or integrin αIIb-deficient BMMCs stimulated by 10 ng/ml IL-3 plus 100 ng/ml SCF for 5 days in BSA- or FB-coated plates. B, β-hexosaminidase release of IgE-sensitized WT or integrin αIIb-deficient BMMCs stimulated by 30 ng/ml TNP-BSA for 60 min in BSA- or FB-coated plates. C and D, IL-6 (C) and TNF-α (D) production of IgE-sensitized WT or integrin αIIb-deficient BMMCs stimulated by 30 ng/ml TNP-BSA for 16 h in BSA- or FB-coated plates. All data are representative of four independent experiments. All data points correspond to the mean ± S.D. * (p < 0.05) indicates statistical differences.