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. 2009 Sep 15;284(45):31463–31472. doi: 10.1074/jbc.M109.030213

FIGURE 5.

FIGURE 5.

Transduction with integrin αIIb(WT) enhanced or suppressed the adhesion to FB or VN, respectively, in integrin αIIb-deficient BMMCs. A, integrin αIIb-deficient BMMCs transduced with integrin αIIb(WT), αIIb(D163A) mutant, or mock were incubated with 5 μg/ml SPE-7 IgE for 60 min in FB- or VN-coated plates. The percentage of adherent cells was measured. Data are representative of three independent experiments. All data points correspond to the mean ± S.D. ** (p < 0.01) and * (p < 0.05) indicate statistical differences. B, integrin αIIb-deficient BMMCs transduced with integrin αIIb(WT), αIIb(D163A) mutant, or mock were incubated with 5 μg/ml SPE-7 IgE for 16 h in FB-coated plates. The amounts of IL-6 released into medium were measured. Data are representative of three independent experiments. All data points correspond to the mean ± S.D. * (p < 0.05) indicates statistical differences.