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Silencing of Mre11 inhibits small deletion of NHEJ in HEK293/pPHW1 cells. A, profiles of NHEJ junctions with or without Mre11 silencing. PCR was performed with primers flanking the two I-SceI sites. B, quantitation of changes in NHEJ. To avoid selection bias, the colonies did not undergo XHATM selection for gpt expression.
