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Protein immunoblots in control and transgenic R6/2 mice brain
| Antibody | Control | Transgenic |
|---|---|---|
| mGluR1a | 100 ± 8.3 | 75.0 ± 8.3 |
| mGluR2/3 | 100 ± 7.7 | 30.8 ± 3.1* |
| mGluR5 | 100 ± 5.3 | 113.2 ± 7.9 |
| NMDA-R1 | 100 ± 24.5 | 87.8 ± 22.4 |
| Ubiquitin | 100 ± 15.0 | 1250 ± 50* |
Numbers represent film optical density (OD) measurements as a percentage of the mean OD readings of the control group (mean ± SEM, n = 6 mice per group).
*P < 0.0001.
