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IL10 suppresses proinflammatory gene transcription. Transcripts for TNFα, ICAM-1, and MMP9 were detected by real-time PCR in either Raw264.7 macrophages or BMDMs treated with medium alone, AcLDL, IL10, or ACLDL plus IL10 for 24 h. The results are representative of at least three independent experiments, and values are expressed as the -fold change in abundance ± S.E.
