Table 4.
Relative Risk and 95% Confidence Intervals for the Association Between Waist Circumference, Hip Circumference, Waist/Hip Ratio, and Waist/Height Ratio and B-Cell Non-Hodgkin Lymphoma Risk Among Women in the California Teachers Study, 1997–2007
Variable | Person-Years | All Cases |
Diffuse Large B-Cell |
Follicular |
CLL/SLL |
||||||||
Cases (n = 377) | Relative Risk | 95% Confidence Interval | Cases (n = 99) | Relative Risk | 95% Confidence Interval | Cases (n = 85) | Relative Risk | 95% Confidence Interval | Cases (n = 81) | Relative Risk | 95% Confidence Interval | ||
Waist circumference, ma | |||||||||||||
<0.74 | 200,090 | 67 | 1.01 | 0.72, 1.41 | 17 | 0.78 | 0.41, 1.48 | 11 | 0.67 | 0.31, 1.42 | 17 | 1.14 | 0.58, 2.25 |
0.74–0.81 | 194,095 | 85 | 1.00 | Referent | 26 | 1.00 | Referent | 22 | 1.00 | Referent | 19 | 1.00 | Referent |
0.82–0.89 | 164,529 | 76 | 0.84 | 0.61, 1.15 | 20 | 0.78 | 0.43, 1.43 | 15 | 0.62 | 0.32, 1.23 | 18 | 0.89 | 0.46, 1.73 |
>0.89 | 177,277 | 111 | 1.03 | 0.74, 1.44 | 27 | 0.92 | 0.48, 1.74 | 30 | 1.02 | 0.53, 1.97 | 22 | 0.99 | 0.49, 2.02 |
Unknown | 94,628 | 38 | 9 | 7 | 5 | ||||||||
Ptrend | 0.76 | 0.72 | 0.25 | 0.62 | |||||||||
Hip circumference, ma | |||||||||||||
<0.95 | 205,668 | 88 | 1.14 | 0.81, 1.59 | 24 | 0.88 | 0.47, 1.65 | 18 | 1.62 | 0.75, 3.52 | 25 | 1.38 | 0.70, 2.71 |
0.95–1.00 | 169,586 | 70 | 1.00 | Referent | 22 | 1.00 | Referent | 12 | 1.00 | Referent | 16 | 1.00 | Referent |
1.01–1.07 | 189,641 | 91 | 1.03 | 0.75, 1.43 | 22 | 0.85 | 0.46, 1.59 | 22 | 1.34 | 0.65, 2.78 | 15 | 0.77 | 0.37, 1.60 |
>1.07 | 169,403 | 89 | 1.15 | 0.79, 1.66 | 20 | 0.85 | 0.41, 1.76 | 27 | 1.77 | 0.80, 3.91 | 20 | 1.40 | 0.65, 3.05 |
Unknown | 96,321 | 39 | 11 | 6 | 5 | ||||||||
Ptrend | 0.98 | 0.85 | 0.64 | 0.98 | |||||||||
Waist/hip ratioa | |||||||||||||
<0.76 | 198,768 | 61 | 0.92 | 0.65, 1.30 | 18 | 1.25 | 0.63, 2.48 | 13 | 0.66 | 0.33, 1.32 | 12 | 0.81 | 0.38, 1.73 |
0.76–0.79 | 172,577 | 70 | 1.00 | Referent | 15 | 1.00 | Referent | 21 | 1.00 | Referent | 16 | 1.00 | Referent |
0.80–0.85 | 182,829 | 92 | 1.00 | 0.73, 1.37 | 23 | 1.22 | 0.63, 2.34 | 15 | 0.57 | 0.29, 1.11 | 24 | 1.12 | 0.59, 2.11 |
>0.85 | 177,793 | 112 | 0.94 | 0.69, 1.29 | 32 | 1.35 | 0.71, 2.55 | 28 | 0.83 | 0.45, 1.51 | 23 | 0.82 | 0.42, 1.59 |
Unknown | 98,652 | 42 | 11 | 8 | 6 | ||||||||
Ptrend | 0.97 | 0.56 | 0.55 | 0.77 | |||||||||
Waist/height ratiob | |||||||||||||
<0.45 | 204,921 | 71 | 1.10 | 0.79, 1.53 | 18 | 0.78 | 0.42, 1.44 | 12 | 0.78 | 0.37, 1.65 | 20 | 1.66 | 0.84, 3.28 |
0.45–0.48 | 175,034 | 76 | 1.00 | Referent | 26 | 1.00 | Referent | 18 | 1.00 | Referent | 15 | 1.00 | Referent |
0.49–0.55 | 171,804 | 84 | 0.86 | 0.63, 1.18 | 18 | 0.56 | 0.30, 1.04 | 22 | 0.93 | 0.49, 1.77 | 18 | 0.94 | 0.47, 1.89 |
>0.55 | 182,083 | 106 | 0.85 | 0.61, 1.18 | 27 | 0.69 | 0.37, 1.28 | 25 | 0.78 | 0.39, 1.54 | 23 | 0.98 | 0.48, 2.02 |
Unknown | 96,777 | 40 | 10 | 8 | 5 | ||||||||
Ptrend | 0.16 | 0.57 | 0.91 | 0.18 |
Abbreviations: CLL, chronic lymphocytic leukemia; SLL, small lymphocytic lymphoma.
Adjusted for height, weight at cohort entry, age at menarche (≤11, 12, ≥13 years, never had period, missing), and long-term strenuous plus moderate physical activity.
Adjusted for weight at cohort entry, age at menarche (≤11, 12, ≥13 years, never had period, missing), and long-term strenuous plus moderate physical activity.