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Study-specific (squares) and meta-analysis (diamond) odds ratios for colorectal cancer among persons with the methylenetetrahydrofolate reductase (MTHFR) 677CT genotype—CT versus CC. Meta-analysis estimate for the CT genotype versus the CC genotype: P = 0.57; Q = 32.887; P = 0.240; I2 = 15%, 95% confidence interval (CI): 0, 46. Horizontal lines, 95% CI.
