Table 2.
InVitro antimalarial activity of the investigated extracts and phytochemical screening
| Plant name | Extracts | Yield of extract (%) | IC50 (µg/ml) | 100% SMI (µg/ml) | Active constituents |
|---|---|---|---|---|---|
| Acalypha fruticosa | MeOH | 13.4 | 10.7 | 125 | Tannins, terpenoids, flavonoids |
| H2O | 8.0 | 1.6 | 7.8 | Proteins, polysaccharides | |
| Azadirachta indica | MeOH | 10.9 | 16.9 | – | Flavonoids, terpenoids |
| H2O | 4.9 | 2.0 | 7.8 | Polysaccharides, proteins, tannins | |
| Boswellia elongata | MeOH | 8.9 | 26.7 | – | Terpenoids |
| H2O | 5.7 | 27.1 | – | Tannins, polysaccharides | |
| Cissus rotundifolia | MeOH | 10.7 | 58.0 | – | Steroids, flavonoids |
| H2O | 6.9 | 34.7 | – | Proteins | |
| Dendrosicyos socotrana | MeOH | 4.2 | 20.0 | – | Terpenoids |
| H2O | 10.9 | 2.3 | 7.8 | Proteins, polysaccharides | |
| Echium rauwalfii | MeOH | 8.2 | 48.3 | – | Terpenoids, flavonoids, alkaloids |
| H2O | 8.7 | 18.8 | – | Polysaccharides | |
| Chloroquine | 0.2 | 12.5 |
There is no complete schizont maturation inhibition until the highest concentration that was used in this investigation (125 µg/ml)for cells with dash.
MeOH, methanol extract; H2O, aqueous extract; IC50, inhibition concentration 50; SMI, Schizonts maturation inhibition.