Table 2.
Summary of structural characteristics of MOLM-13
| Structural characteristics: | control | khat | CPT |
|---|---|---|---|
| Normal mitochondria | + + + | + | + +(+) |
| Presence of ER | + + + | + + | + + |
| Ribosomal clustering | - | + | + |
| Presence of microvilli | + + + | + | + |
| Cytosolic vacuolization* | + | + + + | + + |
| Nuclear margination* | - | +++ | - |
| Nuclear fragmentation* | - | + | + + + |
* scores based on khat/CPT treated cells in late phases of cell death
Based on TEM pictures different structural characteristics of MOLM-13 cells following khat (200 μg/ml) and CPT (0.1 μM) treatment were compared to controls and scored (n = 60).