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. 2000 Aug 15;97(18):10220–10224. doi: 10.1073/pnas.170219997

Figure 3.

Figure 3

The V. cholerae toxR+ strain expressing OmpT in place of OmpU demonstrates a colonization defect. Assay was performed as described in Materials and Methods. Strain KKV780 (ΔompU) carrying either plasmid pKEK253 (Up-U) or pKEK257 (Up-T) was coinoculated with isogenic strain KKV598 (O395 ΔlacZ). The competitive index is the ratio of output mutant/wild type (recovered from small intestine) divided by the ratio of input mutant/wild type (inoculated into mouse); thus, if a mutant strain has no colonization defect, we expect a competitive index close to 1. Data points represent individual mice. Value for colonization of KKV780/Up-T had a P value < 0.01 when compared with the value for colonization of KKV780/Up-U by using the Student's two-tailed t test.