Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
IL-18 chimeras help define binding epitopes. a, human IL-18 and six human (NH2 terminus)/murine (COOH terminus) chimeras (14). b, murine IL-18 and four murine (NH2 terminus)/human (COOH terminus) chimeras. Human sequences are shown as white boxes; murine sequences are black. Residue ranges, the first mature IL-18 residue following caspase-1 cleavage (blue triangle), and epitope tags are noted for each chimera. NT, not tested.
