TABLE 2.

Polar or charged interactions between IL-18 and 125-2H

IL-18 residue/atom	125-2H residue/atom	Distance
		Å
Primary Loop
Lys176 Nζ	SerL53 Oγ	2.9
Asp178 O	ArgL46 Nη1/2	2.8/2.8
Glu179 Oϵ1	ArgH101 Nη1	2.8
Glu179 Oϵ2	ArgH94 Nϵ	2.8
Leu180 N	GlyH95 O	3.2
Gly181 N	TyrH35 Oη	2.9
Gly181 O	PheH33 N	2.9
Arg183 N	AspH31 O	3.0
Arg183 Nη1	ThrH30 O	2.9
Secondary loop
Arg140 Nη2	AlaL92 O	2.9
His145 Nϵ2	AspH50 Oδ1	2.8
Lys148 Nζ	AspH52 Oδ2	2.7
Other loops
Glu152 Oϵ1	LysL32 Nζ	2.8
Glu157 Oϵ2	SerL31 Oγ	2.6