TABLE 1.

Characteristics of male C57BL/6J and SJL/J mice in fed and fasted conditions

Male C57BL/6J and SJL/J mice (10 weeks of age) were fed a chow diet ad libitum or fasted for 24 h prior to study. Each value represents mean ± S.E. of values from 4–6 mice. Asterisks denote level of statistical significance (Student's t test) between fed and fasted mice of the same strain, *, p < 0.01; **, p < 0.001.

Parameter	C57BL/6J		SJL/J
	Fed	Fasted	Fed	Fasted
Total body weight (g)	23.9 ± 0.4	17.0 ± 0.2*	23.2 ± 0.5	18.5 ± 0.6*
Total body fat (g)a	1.63 ± 0.17	0.69 ± 0.12*	1.03 ± 0.14	0.35 ± 0.03*
Total lean weight (g)a	17.9 ± 0.42	14.6 ± 0.38*	17.5 ± 0.56	14.1 ± 0.50*
Liver weight (g)	1.2 ± 0.1	1.0 ± 0.03*	1.4 ± 0.03	0.9 ± 0.04*
Epididymal fat pad weight (g)	0.25 ± 0.01	0.08 ± 0.01**	0.21 ± 0.03	0.07 ± 0.01**
Total body TG (g)b	1.7 ± 0.1	0.58 ± 0.1**	1.0 ± 0.2	0.47 ± 0.1*
Total liver TG (g)b	0.015 ± 0.002	0.079 ± 0.011*	0.008 ± 0.001	0.012 ± 0.003
Liver TG content (mg/g)b	7.0 ± 0.72	97 ± 14**	5.8 ± 0.18	5.4 ± 0.79
Liver cholesterol content (mg/g)b	2.1 ± 0.13	3.5 ± 0.31	2.6 ± 0.09	3.3 ± 0.12
Serum cholesterol (mg/dl)	85 ± 6.2	92 ± 4.2	107 ± 5.3	105 ± 3.1
Serum TG (mg/dl)	68 ± 2.2	68 ± 4.4	141 ± 24	33 ± 4.7*
Serum free FA (mm)	0.59 ± 0.02	1.3 ± 0.13*	0.60 ± 0.07	0.57 ± 0.08
Serum glycerol (mg/dl)	3.4 ± 0.55	2.5 ± 0.09	3.2 ± 0.08	2.2 ± 0.40
Serum β-hydroxybutyrate (mm)	0.25 ± 0.04	2.5 ± 0.15**	0.28 ± 0.04	0.81 ± 0.22
Blood glucose (mg/dl)	132 ± 5	70 ± 1*	136 ± 8	111 ± 6
Plasma insulin (ng/ml)	0.8 ± 0.14	0.1 ± 0.01**	0.9 ± 0.14	0.1 ± 0.01**
Plasma leptin (ng/ml)	2.0 ± 0.53	0.7 ± 0.13**	2.7 ± 0.71	0.5 ± 0.24**
Plasma ASTc (unit/liter)	94 ± 20	143 ± 11	130 ± 13	114 ± 8
Plasma ALTd (unit/liter)	75 ± 5.7	96 ± 5.1	99 ± 9.2	89 ± 12

^a Value determined by NMR.

^b Value determined by extraction and chemical measurement.

^c AST, aspartate aminotransferase.

^d ALT, alanine aminotransferase.