Table 3. Comparative analysis of REST and CoREST promoter occupancy and corresponding gene expression profiles during neuronal developmental transitions.

		REST	CoREST
A	B	+/−	+/−
NSC	MSN
No	Yes	28/53	38/51
Yes	No	75/30	114/139
NSC	CHOLN
No	Yes	69/40	64/19
Yes	No	49/22	138/67
RG	GLUTN
No	Yes	58/20	39/4
Yes	No	25/27	41/21
N/OP	GABAN
No	Yes	118/160	233/218
Yes	No	15/29	42/44

We evaluated specification of neuronal subtypes from their most proximate progenitors, including the developmental transition of specific NSC species into their corresponding mature neuronal subtypes (CHOLNs and MSNs), of radial glia (RG) into GLUTNs, and of bipotent neuronal-OL progenitors (N/OPs) into GABANs. The absence or presence of REST and CoREST promoter occupancy for target genes within each cell type are indicated by no and yes, respectively. Each pair of numbers represents genes up regulated and down regulated (+/−), respectively, during the transition from the proximal progenitor (column A) to its immediate progeny (column B).