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Schematic Model of the Effects on Cell Wall Integrity and Pathogenesis of Protein O-Mannosylation in U. maydis.
Deletions of pmt family members in U. maydis alter both cell wall integrity and maize tumor formation. Elimination of KRE2/MNT1 family members suggests they are essential for maintaining cell wall integrity but not for virulence. The addition of the first three mannose residues is sufficient for the fungus to exhibit normal growth and pathogenic development.
