Table 1. Correlation coefficients for the relationships between aberrant crypt foci and indices and measures of insulin resistance and insulinaemia in Fischer 344 rats initiated by azoxymethane and given diets differing in calorie and saturated fat content (Koohestani et al. [29]) or saturated fat content (Tran et al. [33]).

ACF, aberrant crypt foci; AUC, area under the curve.

Study	Correlation with ACF size/number	Significance
Koohestani et al. [29] (n=98)
Fasting plasma insulin	0.39	<0.01
OGTT glucose AUC	0.67	<0.001
Tran et al. [33] (n=24)
OGTT 180 min insulin	0.42	<0.05
Clamp insulin sensitivity	−0.52	<0.01