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. 2009 Nov 16;118(Pt 4):269–279. doi: 10.1042/CS20090318

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© 2010 The Author(s) The author(s) has paid for this article to be freely available under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons.org/licenses/by-nc/2.5/) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(A) In vitro autoradiograph showing ACE radiolabelling in the rat kidney. The white colour denotes the highest density of labelling, whereas the black colour represents background labelling. Sections from Control (Sham) rat kidney and STNx kidney without and with ramipril treatment are shown. In the Control kidney, there is abundant ACE radiolabelling of the inner cortex and outer stripe of the outer medulla. STNx increases ACE radiolabelling, which was reduced by ramipril. (B) Relative quantification of ACE radiolabelling in the inner cortex of the rat kidney expressed as a percentage of that in Control rats. ***P<0.001 compared with Control vehicle ^###P<0.001 compared with appropriate vehicle-treated rats (n=5/group).