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. 2009 Sep 28;158(5):1210–1226. doi: 10.1111/j.1476-5381.2009.00392.x

Figure 1.

Figure 1

Dose-dependent effects of i.v.-injected (A,B) alosetron, (C,D) cilansetron and (E,F) tegaserod on mesenteric blood flow (MBF, left panels) and mesenteric vascular conductance (MVC, right panels). The doses of the drugs are indicated below the panels: 0 refers to the effects of vehicle. The basal values of the cardiovascular parameters were recorded and averaged during the 25–10 min period pre injection and set as 100%. The values recorded and averaged during the 5–20 min and 35–50 min periods post injection are expressed as a percentage of the baseline recordings. Means + SEM, n= 6–9. *P < 0.05, **P < 0.01 versus basal (one-way anova for repeated measures followed by the Bonferroni test).