Table 1.

Effects of amlodipine, cilnidipine and candesartan on the beat-to-beat variability of the monophasic action potential (MAP) duration in the chronic atrioventricular block dogs

	Amlodipine			Cilnidipine			Candesartan
	C	2W	4W	C	2W	4W	C	4W
STV (ms)	3.8 ± 0.6	4.3 ± 1.1	5.0 ± 0.7	4.2 ± 1.2	1.8 ± 0.4*	2.2 ± 0.4*	4.1 ± 0.8	5.2 ± 0.9
LTV (ms)	2.4 ± 0.4	3.1 ± 1.2	3.3 ± 0.8	2.0 ± 0.5	1.4 ± 0.3	1.7 ± 0.3	2.6 ± 0.6	3.3 ± 0.6

Short-term variability (STV) and long-term variability (LTV) of the MAP duration in the amlodipine and cilnidipine groups were obtained at pre-drug control (C) and 2 weeks (2W) and 4 weeks (4W) after the start of drug administration, whereas those in the candesartan group were obtained at pre-drug control and 4 weeks after the start of drug administration. Data are presented as the mean ± SEM.

^*P < 0.05, compared with corresponding pre-drug control value.